A historical company-documentation page presents material titled Tribestan Effect on the Concentration of Some Hormones in the Serum of Healthy Subjects, attributed to S. Milanov, A. Maleeva and M. Taskov.
Historical source material: This page presents earlier research documentation for educational and documentary use. It is not current prescribing information, a treatment recommendation or a substitute for the leaflet supplied with a current package.
Study design described in the source
| Participants | 16 healthy subjects: 8 male and 8 female, aged 28–45 years. |
|---|---|
| Historical administration schedule | 250 mg, three times daily for 5 days, as described in the earlier source. |
| Sampling | Serum samples were obtained before and after the period described, at 8 a.m. and noon. |
| Measurements | Selected hypophyseal, sexual and adrenal hormones, using radioimmune tests described in the source. |
Historical interpretation
The source reports changes in selected measurements along the hypophyseal-gonadal axis and states that the values remained within physiological limits. Because this was a small exploratory source document and the material is historical, the findings should not be generalized into a personal prediction or treatment recommendation.
